Genetic resistance factors and antimicrobial resistance phenotypes in methicillin-resistant Staphylococcus aureus isolates of animals and humans
Peer-Reviewed Publication
Updates every hour. Last Updated: 24-Apr-2025 03:08 ET (24-Apr-2025 07:08 GMT/UTC)
A baseline for broader gene sequencing based on One Health studies to the emergence of resistance, guides for specific therapies, hospital antibiotic usage/stewardship, and target-specific infection control measures are provided.
We have developed a dual bio-/photo-catalytic system for achieving enantioselective hydroamination of enamines, which can provide easy access to chiral vicinal diamines. These reactions proceed efficiently under green light excitation and exhibit excellent enantioselectivities (up to 99% enantiomeric excess).We have developed a dual bio-/photo-catalytic system for achieving enantioselective hydroamination of enamines, which can provide easy access to chiral vicinal diamines. These reactions proceed efficiently under green light excitation and exhibit excellent enantioselectivities (up to 99% enantiomeric excess).
A groundbreaking study introduces a novel Transformer-based time-series framework designed to predict daily risk alerts for sepsis patients in the Intensive Care Unit (ICU). This model, leveraging sequential data from the eICU database, dynamically captures evolving health trajectories, enabling real-time identification of high-risk patients and actionable insights for personalized interventions. The study, titled “Predictive model for daily risk alerts in sepsis patients in the ICU: visualization and clinical analysis of risk indicators” published in Precision Clinical Medicine February 8, 2025, demonstrates exceptional predictive power, with an AUC increasing from 0.87 on admission day to 0.92 by day 5, offering a new paradigm for ICU prognostics.
A new study reveals that Epstein-Barr virus (EBV) infection exacerbates ulcerative colitis (UC) by driving macrophage pyroptosis through the upregulation of glycolysis. This finding provides a potential therapeutic target for mitigating EBV-induced intestinal inflammation. The study, titled "Epstein-Barr virus infection exacerbates ulcerative colitis by driving macrophage pyroptosis via the upregulation of glycolysis," was published on January 21, 2025, in Precision Clinical Medicine.
A recent review in Engineering presents new methods for enhancing chiral optical signals. Chirality is important in many fields, but its optical signals are weak and hard to measure. The research covers strategies like tailoring optical fields, using photonic resonance, orbital angular momentum (OAM) beams, metasurfaces with bound states in the continuum (BICs), and nonlinear optics. These methods offer new ways to study chiral optics, though challenges remain.
A team from China Agricultural University has developed a novel synergetic cooling and charging strategy for high-power direct current fast charging in electric vehicles. Published in Engineering, the approach uses a gallium-based liquid metal flexible charging connector (LMFCC). This new solution aims to overcome the challenges of thermal shocks and inefficient cooling during high-current charging, with promising results in improving charging system performance.