LPL activity remodeling involves browning of WAT
Peer-Reviewed Publication
Updates every hour. Last Updated: 20-Apr-2025 00:08 ET (20-Apr-2025 04:08 GMT/UTC)
They found that prolonged cold exposure reverses feeding-regulated LPL activity during browning in WAT.
The review provides a detailed overview of the current understanding of RNA modifications in cancer, emphasizing the potential of targeting these modifications for therapeutic intervention. It also points to the need for further research to uncover the full spectrum of regulatory mechanisms and their implications in cancer biology.
Researchers from Jiangsu University, China, have successfully resolved the relationships among five major mesangiosperm lineages using genome-scale data and advanced modeling techniques. Their findings highlight the effectiveness of accounting for compositional heterogeneity in models to better capture the complexities of rapid plant radiations.
Four new lactones including hypomonacid A (1) and hypomonone A–C (4–6), as well as nine known polyketide analogues (2–3 and 7–13) were obtained from endophytic fungus Hypomontagnella sp. TX-09 derived from Santalum album. Their planar structures were extensively established by analyzing HRESIMS and NMR spectroscopic data. Stereochemistry of new compounds was determined by X-ray diffraction analysis and modified Mosher’s method in combination with quantum-chemical ECD calculation. In addition, compounds 1 and 2 showed anti-inflammatory activity by inhibition of lipopolysaccharide (LPS)-induced NO production in RAW264.7 cells at 50 μmol/L without cytotoxicity. Among them, compound 1 inhibited the production of LPS-stimulated inflammation in mouse macrophage RAW264.7 cells by suppressing the expression of iNOS, TNF-α, IL-1β, and IL-6.
A team of researchers has undertaken a study of the future of carbon anodes for lithium-ion batteries. Their review provides a comprehensive overview of the progression in carbon anode development and the current status of their industrialization. This study underscores the critical role of interphase regulation engineering in advancing lithium-ion battery technology.
A collaborative research team led by Professor Yang Hai from the Hong Kong University of Science and Technology, Assistant Professor Ke Jintao from the University of Hong Kong, and Research Assistant Professor Feng Siyuan from the Hong Kong Polytechnic University has developed an open-source, multi-functional simulation platform for on-demand ride service operations. This platform aims to provide an efficient and effective model/algorithm testing environment for researchers and industry professionals.
In a study published in SCIENCE CHINA Chemistry, researchers have showcased the exceptional catalytic performance of a Pt@MFI catalyst in the co-conversion of methane and hexane. The study delves into the influence of K on the size and electronic properties of Pt encapsulated in MFI zeolites, leading to the effective dispersion and stabilization of Pt clusters and, consequently, enhanced catalytic activity. Furthermore, the research employs isotopic labeling and solid-state NMR techniques to elucidate the methane participation in the co-aromatization process.