A pivotal study unveils a novel approach to combating gray mold, a devastating pathogen for grapevines.

This study focused on the effects of the combination of baicalin (BC) and gardenoside (GD) (7:3) on blood-brain barrier (BBB) permeability, brain tissue water content, and aquaporin-4 (AQP-4) expression in rats with cerebral ischemia-reperfusion (I/R) injury. The previous research conducted by the investigators demonstrated that the combination of BC and GD (7:3) has anti-ischemic properties. Further research was conducted to determine the mechanism underlying the reduction in cerebral edema.

Scientists are making waves with a novel therapy for metastatic colorectal cancer (mCRC) that combines two powerful antibodies—one targeting epidermal growth factor receptor (EGFR), the other programmed cell death 1 (PD-1).

In a paper published in SCIENCE CHINA Chemistry, two ion-intercalated iso-structural silver(I)-based coordination networks were prepared, with counterions/intercalants as the sole influencing factor, to clarify their effects for the electrocatalytic CO2 reduction reaction.

In a paper published in SCIENCE CHINA Chemistry, a series of thermodynamically stable 2D cluster-based metal-organic frameworks (MOFs) Fe_n-(pyz) (n = 1~6) with room-temperature ferrimagnetism has been proposed based on first principles calculations. The strong d–p spin exchange interactions between the clusters and pyrazine ligands lead to robust ferrimagnetic ordering. Interestingly, altering the size of Fe_n clusters in Fe_n-(pyz) (n = 1~6) MOFs results in diverse functional spintronic properties, including bipolar magnetic semiconductors (BMS), half semiconductors (HSC) and Dirac half metals (HM).

Drug-induced liver injury (DILI) can present as a chronic phenotype or acute course. However, there is a lack of research on the underlying mechanisms of chronic DILI as well as the definition of cut-off point. We aimed to profile holistic metabolic characteristics of chronic DILI and provide evidence for the cut-off point by serum metabolomics.

A study led by William & Mary's Batten School & VIMS scientists has shown that purple marsh crabs can significantly disrupt carbon cycling in salt marshes along the East Coast of the U.S.

In a paper published in SCIENCE CHINA Chemistry, a step-scheme (S-scheme) heterojunction involving a donor-acceptor (D-A) conjugated polymer and manganese cadmium sulfide (BTz@MCS) has been fabricated to achieve efficient photocatalytic H₂O₂ production in a non-sacrificial system. The high photocatalytic performance of the developed catalyst is attributed to well-designed S-scheme heterojunctions with improved charge separation and transfer.

In a paper published in SCIENCE CHINA Chemistry, an indium-involved modification strategy is employed to address the instability of sulfide electrolyte and Lithium metal. The optimized doping yields a high Li-ion conductivity of 7.5 mS cm⁻¹ for Li_5.54In_0.02PS_4.47O_0.03Cl_1.5 electrolyte, accompanied by enhanced endurance against air/moisture and bare Li metal. Additionally, a composite layer comprising Li–In alloy and LiF phases is generated on the surface of lithium metal anode via the reaction between InF₃ and molten Li. Consequently, the combination of the Li_5.54In_0.02PS_4.47O_0.03Cl_1.5 electrolyte and the InF₃@Li anode provides exceptional electrochemical performances in both symmetric cells and solid-state lithium metal batteries across different operating temperatures.