Scientists reveal links between KLF12 and miscarriage, enabling future targeted prevention
Peer-Reviewed Publication
Updates every hour. Last Updated: 24-Apr-2025 03:08 ET (24-Apr-2025 07:08 GMT/UTC)
A study in Reproductive and Developmental Medicine links elevated levels of the KLF12 protein to impaired placental development, a major cause of unexplained miscarriages affecting 15% of pregnancies. Researchers found higher KLF12 levels in miscarriage cases, which inhibit the GCM1 gene critical for placental cell fusion. KLF12 could serve as a biomarker for miscarriage risk, and targeting its regulation may improve placental function and reduce miscarriages.
Researchers from the University of Science and Technology of China have uncovered the electrodissolution mechanism of zinc electrodes in aqueous zinc-based batteries, providing new insights for improving zinc electrode reversibility. The findings were published in Science Bulletin under the title "Electrodissolution-Driven Enhancement in Zn Electrode Reversibility."
Asynchronous dual-comb generated in single laser cavity offer potent tools for simplified coherent measurements, owing to the common mode rejection which spares the sophisticated locking systems. However, the limited dimensional inhomogeneity in monolithic cavity induces relatively small repetition-rate-difference, hindering high-speed measurements. In a recent research, a monolithic linear fiber laser with integrated multifunctional device employing polarization multiplexing is proposed and demonstrated for dual-comb acquisition speed enhancement. By tuning the inherent the integrated device, controllable asynchronous harmonic mode-locking gets boosted, which enables the multiplication of the equivalent repetition-rate-difference and produces more temporal interferograms via least common multiple principles. Harmonic-repetition-rate up to 2.3 GHz and acquisition speed over 244 kHz are obtained in experiments, faster by 2 orders of magnitudes than previous single-fiber-cavity dual-combs.
A new study reveals that a region in China’s Turpan-Hami Basin served as a refugium, or “Life oasis” for terrestrial plants during the end-Permian mass extinction, the most severe biological crisis since the Cambrian period.
A recent study by Chinese scientists has revealed the intricate molecular machinery driving energy exchange within chloroplasts, shedding light on a key event in the evolution of plant life. Led by FAN Minrui from the Center for Excellence in Molecular Plant Sciences of the Chinese Academy of Sciences, the research elucidates the structure and function of the ATP/ADP translocator—a crucial member of the nucleotide transporter (NTT) family of proteins—which facilitates the transfer of energy across chloroplast membranes.