Allogeneic hematopoietic stem cell transplantation could overcome the poor prognosis of DNMT3AmutNPM1mutFLT3-ITDmut in acute myeloid leukemia: real-world multicenter analysis in China
Peer-Reviewed Publication
Updates every hour. Last Updated: 24-Apr-2025 02:08 ET (24-Apr-2025 06:08 GMT/UTC)
This paper explores the clinical outcomes of allogeneic hematopoietic stem cell transplantation (allo-HSCT) for patients with triple-mutated acute myeloid leukemia (AML), a condition marked by mutations in DNMT3A, NPM1, and FLT3-ITD genes. Despite being classified as intermediate-risk by the European LeukemiaNet (ELN) 2022 risk classification, triple-mutated AML generally has a poor prognosis.
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