An overview of the thermal safety of silicon–carbon anodes is conducted to identify the determinants of material reactivity and heat generation sources. In the hierarchical silicon–carbon anode, surface floating silicon exposed outside the carbon layer is a serious hazard affecting thermal safety, exhibiting a 77% increase in heat release at 100% state of charge. Maximum temperatures of 875.2 °C (532.1 °C for samples with less floating silicon) can be achieved when pouch cells with more floating silicon are conducted in the test of accelerating rate calorimeter. Additionally, this study explored the thermal safety of graphite anodes blending with varying ratios of silicon–carbon materials, confirming the potential safety risks associated with high silicon content lithium-ion batteries. This work presents a comprehensive understanding of the thermal characteristics of high-capacity silicon–carbon anodes, which provides insightful suggestions for enhancing the safety of next-generation silicon-based high-energy-density batteries.

New research has revealed that removing a protein called gasdermin D can protect the liver from inflammation and scarring in alcohol-induced acute-on-chronic liver failure (ACLF). But this comes at a cost: kidney and brain damage increase. The findings suggest that future treatments targeting gasdermin D may need to be organ-specific to avoid doing more harm than good.

Research reveals the main patterns and predictive models of summer vegetation variations in eastern Siberia

A paper published in National Science Review highlights the role of China's natural terrestrial ecosystems (NTEs) as significant sources and sinks of methane (CH₄) and nitrous oxide (N₂O), two potent greenhouse gases. The study, led by Dr. Tingting Li and her team, compiles a new CH₄ and N₂O inventory for China's NTEs from 1980 to 2020, revealing the complex interplay between climate change, land-use changes, and greenhouse gas emissions. The findings underscore the importance of NTEs in global greenhouse gas budgets and provide recommendations for enhancing carbon sequestration and reducing emissions.

Lysosomes are considered as the major degradative site and were recently recognized as dynamic regulators of cellular homeostasis. Many diseases, including cancer, have been linked to functional changes in lysosomes. Natural products and their structural analogs have historically made major contributions to pharmacotherapy. By employing the natural small molecule isowalsuranolide as a chemical probe, the underlying mechanisms of its lysosome-inducing effects were investigated. This study revealed that isowalsuranolide targets TrxR1/2 and triggers lysosomal biogenesis and autophagy via the p53-TFEB/TFE3 axis. This study provides important insight into the lysosomal adaptation mechanism to redox signals and the application of lysosome-inducing agents in the treatment of lysosome-related diseases, including cancer.

A team of researchers has unveiled an innovative diagnostic tool that transforms an everyday toy into a high-tech bacterial detection device. 

This paper reports the discovery of a high-velocity star J07 ejected from globular cluster M15 approximately 21 million years ago, providing strong evidence for the presence of an IMBH constrained to within a few AU of the central region of M15.

A significant discovery has identified a missing "gatekeeper" protein as the root cause of dry mouth in Sjögren's syndrome — a finding that could change the way the disease is treated. 

In a paper published in Science Bulletin, the research teams led by Professor Shunmin He, Professor Runsheng Chen, and Professor Tao Xu from the Institute of Biophysics, Chinese Academy of Sciences, introduced TOAnnoPriDB—a comprehensive resource for annotating and prioritizing non-coding variants across the human genome. This represents the seventh publication from the NyuWa genome project. TOAnnoPriDB integrates trans-omic data from 147 public resources, including six databases previously developed by the team: NyuWa, NONCODE, NPInter, piRBase, SmProt, and LncVar. It features a framework for assessing the functional impact of variants and offers a user-friendly web interface. The database empowers researchers to prioritize and analyze variants, advancing studies on variant functions and disease-related research in humans.