Schizophrenia is a complex psychiatric disorder involving disruptions in neurotransmitters, neurodevelopment, immune function, and genetics. While current antipsychotics mainly target dopamine, they often fail to address negative and cognitive symptoms. This review synthesizes the latest findings on the pathophysiology of schizophrenia and highlights emerging treatments such as TAAR1 agonists, muscarinic modulators, NMDA enhancers, anti-inflammatory agents, and gut-brain axis interventions, paving the way for more precise and effective therapies.

An international research group has examined how many people are affected by preclinical and clinical obesity and what health risks are associated with this. The team led by Prof. Matthias Schulze from the German Institute of Human Nutrition Potsdam-Rehbruecke (DIfE) discovered that almost all people with obesity, i.e., a body mass index (BMI) of at least 30 kg/m², exhibit other measurable indications of increased body fat mass and that around 80 percent of affected individuals are already experiencing health-related complications. The results have been published in the specialist journal Nature Communications.

U.S. counties located closer to operational nuclear power plants (NPPs) have higher rates of cancer mortality than those located farther away, according to a new study led by Harvard T.H. Chan School of Public Health. The study is the first of the 21st century to analyze proximity to NPPs and cancer mortality across all NPPs and every U.S. county. The researchers emphasized that the findings are not enough to establish causality but do highlight the need for further research into nuclear power’s health impacts.

Researchers from several partner institutions of the German Center for Diabetes Research (DZD) have collaborated with international colleagues to develop a new approach for visualizing subtle tissue changes in the pancreas in type 2 diabetes. The results provide new insights into the development of type 2 diabetes. The study has now been published in Nature Communications.

In a study of adults with cancer published by Wiley online in CANCER, those who developed a mental health condition within the first year after their cancer diagnosis had a higher likelihood of dying over the next few years.

Applications are now open for the 2026 EANM Young Scientist Network Award. This new research award, supported by Advanced Accelerator Applications (a Novartis company), aims to accelerate innovative research in alpha radioligand therapy (α-RLT) in prostate cancer. Winners will be recognised across three award categories: Platinum (40,000 euros), Gold (20,000 euros), and Silver (10,000 euros) awards. 

A new study analyzing global Google Trends data from January 2004 to August 2025 finds that online search interest in “crisis hotline” has increased sharply in recent years and tends to rise in the same months as searches about “suicide.” The findings highlight how digital help-seeking signals may provide timely insight into population distress and demand for crisis resources.

Australia’s healthcare system does not adequately protect people experiencing mental illness from high out‑of‑pocket costs, according to a Murdoch University study that is the most comprehensive national analysis of how mental health affects household spending on healthcare to date.