d the challenges of digital transformation in a study by Greta Nasi and Edoardo Ongaro

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In recent years, Italy has become a privileged observatory for analyzing the Neo-Weberian State (NWS), an administrative model combining traditional Weberian elements with new managerial approaches. Initially conceived as a response to the limitations of traditional bureaucracies, this system views hierarchy as the main coordination mechanism, along with a moderate integration of market and network elements. The NWS model is thus proposed as a balance between administrative efficiency and democratic values, centering on the role of law and democratic representation. In the Italian context, the NWS emerges as a resilient yet permeable structure, put to test by populist influences, supranational demands, and technological challenges.

New research shows that cryoablation is a safe and effective approach to close congenital patent foramen ovale (PFO, a small hole in the heart) in patients with atrial fibrillation (AF) undergoing pulmonary vein isolation (PVI) in a single procedure. A new study in Heart Rhythm, the official journal of the Heart Rhythm Society, the Cardiac Electrophysiology Society, and the Pediatric & Congenital Electrophysiology Society, published by Elsevier, details this alternative method to the conventional treatment of implementing a percutaneous metal device for PFO closure, which is associated with adverse events such as infection and arrhythmia.

Substance use disorders are notoriously difficult to treat, as it is challenging to intervene in a drugs’ effect on the brain’s reward pathway without interfering with the pathway’s normal function. In a University of Arizona Health Sciences study, researchers identified a drug that reduced the desire for cocaine in a murine model while keeping the brain’s reward pathways for sugar intact.

New research lays the foundation for potential new diagnostics and therapies.