Article Highlights
Updates every hour. Last Updated: 28-Apr-2025 03:08 ET (28-Apr-2025 07:08 GMT/UTC)
Plant extract inspires new chemistry and new early lead against triple-negative breast cancer
Emory UniversityChemists at Emory University invented a reaction to streamline the total synthesis of a compound, phaeocaulisin A, extracted from a plant used for centuries in traditional Chinese medicine. In laboratory dish experiments conducted with biologists at Winship Cancer Institute of Emory University, the researchers showed the compound’s efficacy against HER2-positive breast cancer cells and triple-negative breast cancer cells. An analogue of the compound the chemists constructed boosted this efficacy.
- Journal
- Journal of the American Chemical Society
- Funder
- U.S. National Science Foundation
SwRI develops tool to predict osteoporotic fracture risk
Southwest Research Institute- Journal
- Bone
From sour to sweet: the genetic pathway of jujube domestication
Nanjing Agricultural University The Academy of ScienceA new study has unveiled the genetic mechanism controlling citric acid content in jujube fruit, identifying a natural mutation in the promoter of the ZjACO3 gene.
- Journal
- Horticulture Research
Mapping the quality of public transportation in Germany
University of KonstanzInteractive maps show the accessibility and quality of public transportation for each house in Germany. Computer scientists at the University of Konstanz developed the maps to enable data-driven simulations for discussing political issues – or just checking the situation in one's own neighbourhood.
Why anti-TNF drugs don’t work for some kids with Crohn's disease
Michigan Medicine - University of MichiganA study from Michigan Medicine researchers has investigated possible genetic factors for drug efficacy for children with Crohn’s disease. In this latest study, HLA DQA1*05 positive children just taking the anti-TNF mediation had the highest rate of drug failure.
- Journal
- The American Journal of Gastroenterology
- Funder
- Leona M. and Harry B. Helmsley Charitable Trust
Unlocking safer batteries: New study uncovers key insights into electrolyte materials for all-solid-state batteries
DOE/Argonne National LaboratoryResearchers at Argonne have discovered that superconducting nanowire photon detectors can also be used as highly accurate particle detectors, and they have found the optimal nanowire size for high detection efficiency.
- Journal
- ACS Materials Letters
Solutions journalism can spur climate action, University of Oregon study finds
University of Oregon- Journal
- Environment and Behavior
Additional steps must be taken besides technological improvements to achieve zero carbon emissions by 2050, Ben-Gurion University of the Negev model shows
Ben-Gurion University of the Negev- Journal
- Nature Sustainability
New insights into how dairy cattle efficiently convert plant biomass into nutrients: unlocking the power of rumen microbiota
Maximum Academic Press- Journal
- Animal Advances