The results suggest that chaperone-mediated autophagy, a cellular ‘selective cleaning’ system, could become a new therapeutic target. The study, published in Acta Neuropathologica Communications, was conducted using human tissues from clinical trials and opens new avenues for the development of treatments to slow the progression of ALS.

Researchers discovered that fur seals that have returned onshore after foraging trips increase their heart rate – a measure of metabolic activity – for prolonged periods. These results imply that time spent on land is not simply spent resting, but actively recovering from physiological stress. For example, they may increase their metabolic rate on land to remove lactic acid and restore oxygen stores in skeletal muscle after diving for food.

Researchers use a light-activated protein to illuminate when embryos can cope with disruptions to cell division.

Differences in brain connectivity are linked to several neurodevelopmental disorders, yet scientists still struggle to determine what changes are shared or unique to each condition. A new study analyzing brain scans from more than 2,100 individuals reveals a common pattern of disrupted neural connectivity across autism, ADHD, and schizophrenia. The research also identifies distinct molecular and cellular signatures for each disorder, offering insight into how complex psychiatric conditions arise from overlapping yet different biological mechanisms.

A team of UCLA researchers has developed a new method to build programmable artificial organelles inside living cells using RNA as both the material and the blueprint. The approach enables researchers to design droplet-like cellular compartments that assemble in predictable ways and can be controlled in how and where they form, as well as what molecules they recruit. 

Tiny flexible lasers can be used to measure forces inside living cells, which could help illuminate various biological processes, including those involved in early development and tumor progression.

Sequencing environmental DNA – or eDNA – from the East River in New York City can effectively monitor human diets and local wildlife, as well as the river’s fish populations, report Mark Stoeckle and Jesse Ausubel of The Rockefeller University, U.S., in study publishing April 29, 2026 in the open-access journal PLOS One.

The placenta contracts independently of the rest of the uterine wall, as seen in around 60% of 36 MRI-scanned healthy pregnancies, according to a new study published April 29, 2026 in the open-access journal PLOS One by Louise Dewick of the University of Nottingham, U.K., and colleagues.

Scientists have used an online game to discover the secrets of animal camouflage – such as why tigers have stripes.