A research team led by Prof. CUI Songlin at University of Science and Technology of China (USTC), in collaboration with Prof. ZHOU Meng's team from Beijing Information Science and Technology University (BISTU) has proposed a new strategy for designing pure-red organic light emitting diodes (OLED) materials. These materials have achieved a milestone with electroluminescence efficiencies exceeding 43%, marking a significant step towards high-performance ultrahigh-definition OLED displays. The study was published online in the Journal of the American Chemical Society.

Researchers at the Institute of Modern Physics (IMP) of the Chinese Academy of Sciences, together with their collaborators, have achieved the first precise mass measurements of several exotic atomic nuclei. Using this mass data, they have determined the proton dripline for the elements aluminum, phosphorus, sulfur, and argon, and have proposed a new approach to uncovering proton halo structures.

The paper explores the unique properties of optically active crystals with screw symmetries. These crystals exhibit nonlocal super-dispersion, meaning their polarization rotation properties strongly depend on the wavelength. This nonlocal response allows for the development of a novel camera, the "Nonlocal-Cam." Unlike traditional cameras, the Nonlocal-Cam captures the spectral and polarimetric components of light, providing additional information about the scene. This technology has potential applications in various fields, including biology, machine vision, and remote sensing.

A pivotal study unveils a novel approach to combating gray mold, a devastating pathogen for grapevines.

Scientists are making waves with a novel therapy for metastatic colorectal cancer (mCRC) that combines two powerful antibodies—one targeting epidermal growth factor receptor (EGFR), the other programmed cell death 1 (PD-1).

In a paper published in National Science Review, a Chinese team of scientists present patterns of mercury accumulation in wetlands across the Qinghai-Tibet Plateau. They reveal that glacier melting and permafrost thawing forced by global warming, coupled with human influences, alter geomorphology and hydrology in wetlands. This finally affects mercury transport and accumulation in wetlands of the Qinghai-Tibet Plateau.

In a paper published in National Science Review, an international team of scientists present a novel microstructure modulation strategy that efficiently enhances both the mechanical and thermoelectric performance of bismuth telluride alloy. The improved bismuth telluride demonstrates the capability to fabricate efficient Peltier microcoolers suitable for chip-scale refrigeration.

In a paper published in Science Bulletin, a Chinese team of scientists conducted a GFP-activation assay screening 13 Cas12b nucleases for mammalian genome editing, identifying five active candidates. Candidatus hydrogenedentes Cas12b (ChCas12b) was found to recognize a straightforward WTN (W = T or A) proto-spacer adjacent motif (PAM), thereby dramatically expanding the targeting scope. Upon optimization of the single guide RNA (sgRNA) scaffold, ChCas12b exhibited activity comparable to SpCas9 across a panel of nine endogenous loci. Additionally, the team identified nine mutations enhancing ChCas12b specificity. More importantly, they demonstrated that both ChCas12b and its high-fidelity variant, ChCas12b-D496A, enabled allele-specific disruption of genes harboring single nucleotide polymorphisms (SNPs). These data position ChCas12b and its high-fidelity counterparts as promising tools for both fundamental research and therapeutic applications.