Advancements in diagnostics and therapeutics for cancer of unknown primary in the era of precision medicine
Peer-Reviewed Publication
Updates every hour. Last Updated: 26-Apr-2025 08:08 ET (26-Apr-2025 12:08 GMT/UTC)
In a paper published in MedComm, an international team of scientists provided an overview of the advancements in the diagnostics and therapeutics of cancer of unknown primary (CUP) over the past 50 years. Looking ahead, they propose optimizing diagnostic modalities and exploring further-line treatment regimens as two focus areas for future studies on CUP.
Neuromorphic computing vision is the most promising technological solution to overcome the arithmetic bottleneck in machine vision applications. Towards this goal, Scientists in China proposed a physisorption-assistant optoelectronic synaptic transistor based on Ta2NiSe5/SnS2 heterojunction, which presents tunable synaptic functionality in broadband (375-1310 nm). The physisorption-assistant persistent photoconductivity effect effectively solves the problem of detecting and storing near-infrared light information. The approach offers a route for creating advanced all-in-one neuromorphic sensors and developing neuromorphic computing vision.
Catalyst–support interaction plays a crucial role in improving the catalytic activity of oxygen evolution reaction (OER). Here we modulate the catalyst–support interaction in polyaniline-supported Ni3Fe oxide (Ni3Fe oxide/PANI) with a robust hetero-interface, which significantly improves oxygen evolution activities with an overpotential of 270 mV at 10 mA cm−2 and specific activity of 2.08 mA cmECSA−2 at overpotential of 300 mV, 3.84-fold that of Ni3Fe oxide. It is revealed that the catalyst–support interaction between Ni3Fe oxide and PANI support enhances the Ni–O covalency via the interfacial Ni–N bond, thus promoting the charge and mass transfer on Ni3Fe oxide. Considering the excellent activity and stability, rechargeable Zn-air batteries with optimum Ni3Fe oxide/PANI are assembled, delivering a low charge voltage of 1.95 V to cycle for 400 h at 10 mA cm−2. The regulation of the effect of catalyst–support interaction on catalytic activity provides new possibilities for the future design of highly efficient OER catalysts.
A new method using glycan-coated magnetic nanoparticles (gMNPs) is poised to change the way we detect foodborne pathogens like Escherichia coli and Salmonella in complex food matrices such as melons, lettuce, and raw chicken.
A research paper by scientists at Tianjin University presented an earthworm-inspired multimodal pneumatic continuous soft robot enhanced by wire-winding transmission.