Kyushu University researchers have created a novel “ACTG” naming system for human gene types, and launched the Joint Open Genome and Omics Platform 1.0 (JoGo 1.0), a global database cataloging 4.7 million gene types from more than 19,000 genes. Integrated with other public resources, the platform establishes a universal language for human gene types, empowering applications in fields such as disease research, drug development, and evolutionary biology.

For the first time, real-time imaging tracks what happens to cancer cells arriving in the brain, identifying a new strategy to prevent brain tumors. Published in Cancer Research, a journal of the American Association for Cancer Research, the study identifies two proteins that seed cells use to avoid being destroyed by microglia when they first arrive. By genetically removing these proteins, researchers showed that microglia play a key role in eliminating cancer cells during the early stage of their arrival in the brain.

A new study from Ritsumeikan University reveals how everyday repairs and spatial adjustments help maintain autonomy within a Japanese squatted space. Based on participant observation in the Takayama Architecture Summer School squat, the research shows that social activism can emerge from ordinary acts, such as fixing a door or rearranging a room, enabling diverse groups to coexist and shape their environment without the need for professional expertise

Maintaining long-term health has become a major challenge, driving research into ways to extend “healthspan” rather than lifespan alone. In a recent study, researchers from Japan investigated COX7RP, a mitochondrial protein that promotes the assembly of mitochondrial respiratory supercomplexes essential for efficient energy production. They found that boosting COX7RP improves mitochondrial performance, enhances metabolic health, and significantly prolongs lifespan in mice, opening doors to novel anti-aging interventions and therapeutic strategies for aging-related diseases.

The Jahn–Teller effect is a well-explored phenomenon in solid-state physics. In a new development, researchers from Waseda University, Japan, focused on spinel-type compounds with the formula AV₂O₄, discovering a phenomenon in which a structural phase transition occurs simultaneously with magnetic ordering in Co₁₋ₓFeₓV₂O₄. This innovation holds fundamental scientific interest and is expected to open new avenues for applications in quantum information.

At the base of mossy trees, deep in the mountains of Taiwan and mainland Japan or nestled in the subtropical forests of Okinawa, grows what most might mistake for a mushroom – but what is actually a very unique plant with some of the smallest flowers and seeds in the world. With no chlorophyll to photosynthesize with and no root system to supply it with water from the ground, Balanophora has evolved a series of extreme traits to survive entirely as a parasite on the roots of specific trees. Some species and populations produce seeds only without fertilization (obligate agamospermy) – which is exceedingly rare in the plant kingdom. 

 

Researchers from the Okinawa Institute of Science and Technology (OIST), Kobe University, and the University of Taipei have now joined forces to survey Balanophora across its sparse and inaccessible habitats, upending our understanding of photosynthesis loss in land plants, obligate agamospermy, and the role of the plastids.   

There are plants that are neither green nor sexually reproductive, but precisely because of that they teach us a lot about what it means to be a plant. New research with Kobe University participation took a close look at Balanophora to learn how such non-green, asexual plants evolve and live.

You’ve heard of qubits, now get ready for p-bits! These units form the building blocks of probabilistic computers that can solve certain problems more efficiently than traditional computers. A team of international researchers found a way to do without a power-hungry, bulky, analog component to allow for a fully digital p-bit design.

Computer simulations revealed the detailed mechanism of how the protein "dynamin" works to form small vesicles within cells.

While dynamin uses GTP hydrolysis energy to change shape, it was unclear how this leads to membrane constriction. Simulations showed that instead of simply tightening, dynamin "loosens" (expands) at a certain stage to generate the force needed to narrow the surrounding membrane tube.

This study provides a clearer explanation for membrane deformation and vesicle formation processes in cells, offering insights for artificial nano-device design.

Researchers from The University of Osaka have developed a novel reverse genetics system to study norovirus, the leading cause of gastroenteritis. This efficient system can generate infectious viral particles by simply injecting viral genetic material into zebrafish embryos. They were able to alter the genetic material to create modified viruses, enabling the evaluation of antiviral drugs and novel vaccine development. The advances provided by this new system will have a significant effect on public health.