Starch-based microplastics could cause health risks in mice, study finds
Peer-Reviewed Publication
Wear and tear on plastic products releases small to nearly invisible plastic particles, which could impact people’s health when consumed or inhaled. To make these particles biodegradable, researchers created plastics from plant starch instead of petroleum. An initial study published in ACS’ Journal of Agricultural and Food Chemistry shows how animals consuming particles from this alternative material developed health problems such as liver damage and gut microbiome imbalances.
Cancer diagnoses traditionally require invasive or labor-intensive procedures such as tissue biopsies. Now, research published in ACS Central Science reveals a method that uses pulsed infrared light to identify molecular profiles in blood plasma that could indicate the presence of certain common cancers. In this proof-of-concept study, blood plasma from more than 2,000 people was analyzed to link molecular patterns to lung cancer, extrapolating a potential “cancer fingerprint.”
Researchers have found new compounds that could be used to treat a common breast cancer that can be resistant to hormone therapies, outlined in a paper published in the journal RSC Medicinal Chemistry finding two critical enzymes involved in the production of the hormone oestrogen —aromatase and steroid sulfatase—at the same time.
Results of study led by investigators at the Vall d'Hebron Institute of Oncology (VHIO) show convergent genetic adaptation under hypoxia (lack of oxygen) between populations living at high-altitude in the Himalayan region such as Tibetans and Sherpas, and the development of oxygen-starved cancer cells.
Coupling reactions are essential in the synthesis of pharmaceuticals, agrochemicals, and advanced materials, but traditional methods often rely on costly and environmentally taxing transition metal catalysts. Now, researchers from Japan have reviewed emerging transition metal-free alternatives that align better with green chemistry principles. Their study highlights hypervalent iodine-mediated coupling, a strategy that enables selective bond formation without rare metals. By leveraging diaryliodonium salts, this approach can greatly enhance efficiency and reduce waste in coupling reactions.
Nanoplastics are an increasing threat to the ecosystem; however, their mobility in the soil is still underexplored. Against this backdrop, researchers from Waseda University and the National Institute of Advanced Industrial Science and Technology investigated the adsorption and aggregation behavior of nanoplastics in different types of soil under different pH conditions. The study offers new perspectives on the migration and environmental interactions of nanoplastics, while broadening our knowledge of pollution dynamics and soil contamination processes.
A recent study has used advanced techniques to uncover the role of ultraviolet (UV) light in activating peracetic acid (PAA) to generate powerful radicals, essential for water treatment. By combining in-situ electron paramagnetic resonance (EPR) with density functional theory (DFT) calculation, the researchers identified and analyzed the types and concentrations of radicals produced under different UV wavelengths (185, 254, and 365 nm). The results show that UV light at different wavelengths influences the type and concentration of formed radicals. The study provides new insights into how PAA-based advanced oxidation processes (AOPs) work based on the key radicals identification, offering a solid foundation for optimizing UV-based water purification technologies and potentially expanding their application in environmental remediation areas.