Figure 3: Human CYP enzymes’ metabolite formation activity against chiral PCB atropisomers (IMAGE)

Kobe University

Figure 3: Human CYP enzymes’ metabolite formation activity against chiral PCB atropisomers

Caption

Of the two atropisomers in each chiral PCB, (aR)-CB45 in CB45 and (aS)-CB183 in CB183 are metabolized into hydroxylated metabolites more. In CB91, each atropisomer is metabolized at a similar rate.

Credit

Modified from Inui et al. Environmental Science & Technology, 2022 and Ito et al. Chemosphere, 2022.

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