The Mechanism of Bone Formation Control by SIRT7 (IMAGE)

Kumamoto University

The Mechanism of Bone Formation Control by SIRT7

Caption

When SIRT7 does not work sufficiently, as happens during aging, osteoblasts have difficulty producing bone due to low transcriptional activity of SP7/Osterix, which is thought to cause decreased osteogenesis associated with osteoporosis.

Credit

Dr. Tatsuya Yoshizawa

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