SIRT7による骨形成制御のメカニズム (IMAGE)

Kumamoto University

SIRT7による骨形成制御のメカニズム

Caption

老化した場合などSIRT7が十分に働かない状況では、SP7/Osterixの転写活性が低いために骨芽細胞が骨を作ることが損なわれ、骨形成低下に伴う骨粗相症が引き起こされると考えられます。

Credit

Dr. Tatsuya Yoshizawa

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