Induction of cell senescence by NSD2 inhibition (IMAGE)

Kumamoto University

Induction of cell senescence by NSD2 inhibition

Caption

The NSD2 enzyme acts to prevent cell aging. LEFT: Suppression of the NSD2 gene in fibroblasts arrested cell proliferation. RIGHT: Suppression of the NSD2 gene induces senescent cells with SA-?-galactosidase positivity.

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Professor Mitsuyoshi Nakao

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<p>Left image adapted from fig. S1(f), right image adapted from fig. 1e of <a href="https://onlinelibrary.wiley.com/doi/10.1111/acel.13173">Tanaka et.al. 2020</a>. </p> <p>This image is made available under the terms of <a href="https://creativecommons.org/licenses/by/4.0/">CC by 4.0</a>. Any further distribution of this work must follow the terms of this license. </p>

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