Induction of Cell Senescence by NSD2 Inhibition (IMAGE)

Kumamoto University

Induction of Cell Senescence by NSD2 Inhibition

Caption

The NSD2 enzyme acts to prevent cell aging. LEFT: Suppression of the NSD2 gene in fibroblasts arrested cell proliferation. RIGHT: Suppression of the NSD2 gene induces senescent cells with SA-?-galactosidase positivity.

Credit

Professor Mitsuyoshi Nakao

Usage Restrictions

<p>Left image adapted from fig. S1(f), right image adapted from fig. 1e of <a href="https://onlinelibrary.wiley.com/doi/10.1111/acel.13173">Tanaka et.al. 2020</a>. </p> <p>This image is made available under the terms of <a href="https://creativecommons.org/licenses/by/4.0/">CC by 4.0</a>. Any further distribution of this work must follow the terms of this license. </p>

License

Licensed content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.