Figure 2. Activation of specific neurons and brain circuits through nano-MIND technology (IMAGE)
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Top) 1. Selective expression of nano-magnetoreceptors only in desired target neurons in a mouse model with applied Cre-loxP genetic engineering technology. 2. When rotational magnetic field stimulation is applied, the nano-magnetoreceptors of the target neurons are activated. 3. The brain circuit involving the target neurons is selectively activated and controlled.
Bottom) Expression of nano-magnetoreceptors in the lateral hypothalamus and activation of target neurons. Nano-magnetoreceptors (green) are selectively expressed only in target neurons (red) and their activity increases in response to magnetic field signals.
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Institute for Basic Science
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