Figure 3. Experiment on regulating brain circuits responsible for sociability and emotions using nano-MIND (IMAGE)
Caption
1. Nano-magnetoreceptors generated only in inhibitory neurons of the medial preoptic area (MPOA) selectively activate the inhibitory brain circuit of the MPOA in response to magnetic field signals. This enables the regulation of brain circuits responsible for maternal love and parental behavior.
2. When magnetic stimulation is applied, female mice injected with nano-magnetoreceptors show increased maternal behavior and rescue pup mice to their own nest, despite not being mother mice. In contrast, control female mice show no interest in the pup mice.
3. Only in female mice with applied nano-MIND technology, the brain circuit responsible for maternal love is activated by magnetic stimulation, resulting in the rescue of all pup mice and a more than 4-fold increase in care time compared to regular mice.
Credit
Institute for Basic Science
Usage Restrictions
Attribution Required
License
Original content