Therapeutic potential of EVs. (IMAGE) First Hospital of Jilin University Caption EVs can be used as therapeutical agent or delivery vehicles. As therapeutical agent, EVs are always from stem cells and they can attenuate hepatic inflammation, necrosis and oxidative stress and promote hepatocyte proliferation. As delivery vehicles, EVs loading drugs with genetic or chemical modification target liver to improve fibrosis. EVs, extracellular vesicles; HLSC, human liver stem cell; MSC, mesenchymal stem/stromal cell; PSC, pluripotent stem cell. Credit By Yingying Liu and Lin Wang Usage Restrictions Credit must be given to the creator. Only noncommercial uses of the work are permitted. License CC BY-NC Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.