image: Three-dimensional crystal structure of the target CPSF3 protein (in blue) bound to the AN3661 inhibitor (in yellow) with a scanning electron micrograph background of Cryptosporidium infecting the ileum of an immunocompromised mouse. This material relates to a paper that appeared in the Nov. 6, 2019, issue of Science Translational Medicine, published by AAAS. The paper, by C. Swale at University Grenoble Alpes in Grenoble, France; and colleagues was titled, "Metal-captured inhibition of pre-mRNA processing activity by CPSF3 controls Cryptosporidium infection." view more
Credit: [Credit: C. Swale, F. Laurent, and S. Georgeault]