image: High-resolution microscopy pictures show nuclear shape rescue of cells depleted for Lamin A/C by siRNA upon Remodelin treatment. A non-treated cell is shown on the left and a Remodelin-treated cell is shown on the right. The nucleus is visualized in blue by DAPI. The nucleoli are visualized in green by NAT10 staining. This image relates to a paper that appeared in 2 May, 2014, issue of Science, published by AAAS. The paper, by Delphine Larrieu at the Wellcome Trust/Cancer Research UK (CRUK) Gurdon Institute in Cambridge, UK, and colleagues was titled, "Chemical Inhibition of NAT10 Corrects Defects of Laminopathic Cells." view more
Credit: [Image courtesy of Delphine Larrieu]