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New Drugs for Protein Build-up in the Heart (1 of 4)

Reports and Proceedings

American Association for the Advancement of Science (AAAS)

New Drugs for Protein Build-up in the Heart (1 of 4)

image: Ribbon depiction of the four subunits that comprise the TTR protein tetramer showing the T4 binding sites along the 2-fold axis and the peripherally bound ligands. This image relates to a paper that appeared in the Aug. 24, 2011, issue of Science Translational Medicine, published by AAAS. The paper, by Dr. Mamoun Alhamadsheh of Stanford University Medical School in Stanford, Calif., and colleagues, was titled, "Potent Kinetic Stabilizers That Prevent Transthyretin-Mediated Cardiomyocyte Proteotoxicity." view more 

Credit: Image courtesy of Dr. Stephen Connelly of the Scripps Research Institute


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