New Drugs for Protein Build-up in the Heart (1 of 4) (IMAGE)

American Association for the Advancement of Science (AAAS)

New Drugs for Protein Build-up in the Heart (1 of 4)

Caption

Ribbon depiction of the four subunits that comprise the TTR protein tetramer showing the T4 binding sites along the 2-fold axis and the peripherally bound ligands. This image relates to a paper that appeared in the Aug. 24, 2011, issue of Science Translational Medicine, published by AAAS. The paper, by Dr. Mamoun Alhamadsheh of Stanford University Medical School in Stanford, Calif., and colleagues, was titled, "Potent Kinetic Stabilizers That Prevent Transthyretin-Mediated Cardiomyocyte Proteotoxicity."

Credit

Image courtesy of Dr. Stephen Connelly of the Scripps Research Institute

Usage Restrictions

Please cite the owner of the image when publishing. This image may be freely used by reporters as part of news coverage, with proper attribution. Non-reporters must contact <i>Science</i> for permission.

License

Licensed content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.