image: This illustration shows how the researchers' nanoparticles (DOX-hyd-BSA NPs) selectively kill inflammatory neutrophils to prevent them from invading healthy tissue. The nanoparticles carry doxycycline (DOX) molecules that are held inside albumin (BSA) cells using an acid-sensitive (hyd) bond that releases once inside the neutrophil. This material relates to a paper that appeared in the November 6th, 2019, issue of Science Advances, published by AAAS. The paper, by C.Y. Zhang at Washington State University in Spokane, WA, and colleagues was titled, "Nanoparticle-induced neutrophil apoptosis increases survival in sepsis and alleviates neurological damage in stroke." view more
Credit: [Credit: Zhang <em>et al.</em>, Washington State University]