Amyloid and τ PET imaging in AD in a 72-year-old man with AD dementia. (IMAGE)
Caption
Amyloid and τ PET imaging in AD in a 72-year-old man with AD dementia. (A, B) Axial (A) and coronal (B) PET/CT amyloid images (tracer: florbetapir) show extensive diffuse uptake in the bilateral frontoparietal and temporal lobes. (C, D) Midsagittal (C) and lateral sagittal (D) MRI/PET τ images (tracer: AV-1451) show moderate uptake (arrow) in the temporoparietal lobe including the precuneus and posterior cingulate, representing τ deposits. Although overlap between the τ and amyloid tracers is present, abundant uptake is seen in the lateral temporal lobes with the τ ligand but not with the amyloid ligand.
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Radiological Society of North America
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