Figure 2 (IMAGE)

Pohang University of Science & Technology (POSTECH)

Figure 2

Caption

Signaling, mitochondrial functions, and senescence affected by aging and adipocyte-specific Crtc2 knockout. Adipocyte-specific Crtc2 knockout mice (Crtc2 AKO) resulted in a block of decreased BCAA catabolism (A), activation of mTORC1 (B), diminished mitochondrial functions (C), and the adipocyte senescence (D) caused by aging, effectively preventing the generation of aging-related adipocyte dysfunctions.

Credit

POSTECH

Usage Restrictions

None

License

Licensed content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.