発見した環状ペプチドを提示するファージ(左)およ (IMAGE) Kumamoto University Caption (左)発見した環状ペプチドを提示するファージをマウス血液中に投与し、60分後の脳を解析した結果、脳内にファージが入っていることがわかった。 (右)リポソーム表面に発見した環状ペプチドを付加した修飾リポソームを作成し、マウス血液中に投与した結果、60分後の脳にリポソームが検出された。 Credit Professor Sumio Ohtsuki Usage Restrictions <p>Reprinted from Figs. 5B & 7E of the <a href="https://www.sciencedirect.com/journal/journal-of-controlled-release">Journal of Controlled Release</a>, 321, Yamaguchi, S., Ito, S., Masuda, T., Couraud, P.-O., & Ohtsuki, S, "Novel cyclic peptides facilitating transcellular blood-brain barrier transport of macromolecules in vitro and in vivo," 744-755, Copyright 2020, doi:10.1016/j.jconrel.2020.03.001 with permission from Elsevier. It has been modified in the following manner: The text has been reduced & simplified for use as a press release.</p> <p>This image may not be reproduced without permission from Elsevier.</p> License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.