Phage/liposome Transfer to Mouse Brain (IMAGE)
Caption
(Left) The phages with the new cyclic peptide were intravenously injected into a mouse. Sixty minutes later the brain was analyzed and phages were detected in the brain.
(Right) A modified liposome with the cyclic peptide attached to its surface was prepared and intravenously injected into a mouse. Sixty minutes later the liposome was detected in the brain.
Credit
Professor Sumio Ohtsuki
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<p>Reprinted from Figs. 5B & 7E of the <a href="https://www.sciencedirect.com/journal/journal-of-controlled-release">Journal of Controlled Release</a>, 321, Yamaguchi, S., Ito, S., Masuda, T., Couraud, P.-O., & Ohtsuki, S, "Novel cyclic peptides facilitating transcellular blood-brain barrier transport of macromolecules in vitro and in vivo," 744-755, Copyright 2020, doi:10.1016/j.jconrel.2020.03.001 with permission from Elsevier. It has been modified in the following manner: The text has been reduced & simplified for use as a press release.</p> <p>This image may not be reproduced without permission from Elsevier.</p>
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