Figure 3: Renal Glomerulus (IMAGE)

Kobe University

Figure 3: Renal Glomerulus

Caption

The renal glomerulus slit diaphragm is located in-between the podocyte foot processes and functions as a barrier to prevent protein entering the urine. Nephrin (indicated by the red box), is the most important component protein for the formation of the renal glomerulus slit diaphragm and NPHS1 is the gene that encodes nephrin.

Credit

Kobe University (Slightly altered version of: Tryggvason K et al. Hereditary Proteinuria Syndromes and Mechanisms of Proteinuria. N Engl J Med 2006; 354:1387-1401, Fig.5. Components of the Slit-Diaphragm Protein Complex That Form a Porous Slit-Diaphragm Filter.)

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