Figure 2: Synapse-Specific Memory Erasure (IMAGE)

Japan Science and Technology Agency

Figure 2: Synapse-Specific Memory Erasure

Caption

Mice were exposed to two auditory fear conditioning, separated by five hours. Both memories were encoded by shared neurons in the lateral amygdala (LA) while they were encoded by different neurons in the auditory cortex (AC). Injecting combination of anisomycin+tat-beclin after retrieving certain memory, erased that specific memory without affecting the other linked memory that was stored in the shared neuronal ensemble.

Credit

Kaoru Inokuchi, Kareem Abdou

Usage Restrictions

None

License

Licensed content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.