Scanning a Prostate for Dangerous Mutations (IMAGE)

Cold Spring Harbor Laboratory

Scanning a Prostate for Dangerous Mutations

Caption

Screen shot from a new genome-viewing program (single cell genomic viewer, or SCGV) that displays results of CSHL's innovative method for analyzing diagnostic prostate biopsy results. Arrayed in columns from left to right are genomic profiles of each of several hundred prostate cells sampled from an inidivual's 13 biopsy cores. In the uppermost section note the phylogenetic trees (green) that reflect each cell's copy-number profile. Most of the cells are normal, but two areas of interest are evident (arrows). These are the locations of 2 clones and subclones in the biopsy cores, a strong signal of the presence of cancer.

Credit

Krasnitz Lab, CSHL

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