Overview of Epigenomic Changes in Vascular Endothelial Activation in Response to VEGF Signaling (IMAGE)

Kumamoto University

Overview of Epigenomic Changes in Vascular Endothelial Activation in Response to VEGF Signaling

Caption

Dynamic histone code mapping revealed that endothelial cell (EC) activation was triggered by the bivalent epigenome switch which stimulated angiogenesis related acute transferrin (TF) expression. Then, temporal and special coordinate interaction with NFAT/PTIP and the PRC1.3 variant lead proper VEGF-mediated EC activation.

Credit

Dr. Takashi Minami

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Credit must be given to the creator.

License

CC BY

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