(IMAGE)

Kumamoto University

Caption

On the cover: Kanki and Minami et al. present a global mapping of VEGF-mediated dynamic transcriptional events, focusing on major histone-code profiles using ChIP-seq. They identify a bivalent histone-marked immediate-early transcription factor essential for VEGF-responsive angiogenesis. The cover highlights the retina's non-canonical polycomb 1 (PRC1.3)-mediated proper postnatal vascular network. Colors indicate green, CD31; magenta, isolectin B4.

Credit

Dr. Takashi Minami

Usage Restrictions

Credit must be given to the creator.

License

CC BY

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.