Figure 3 (IMAGE) Osaka University Caption Treatment with an NIK inhibitor significantly reduces the (A) cell proliferation of an intrahepatic cholangiocarcinoma (ICC) cell line and (B) tumor growth of ICC xenografts. Credit © 2022 Yuto Shiode et al., Traf3 inactivation promotes the development of intrahepatic cholangiocarcinoma via NIKmediated hepatocyte transdifferentiation, Hepatology Usage Restrictions Credit must be given to the creator. Only noncommercial uses of the work are permitted. No derivatives or adaptations of the work are permitted. License CC BY-NC-ND Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.