LSD1は、赤芽球性白血病(EL)細胞で解糖系とヘム合成を& (IMAGE)
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LSD1の機能を抑制(LSD1-KD)すると、細胞内へのグルコース(糖)の取り込みが抑制されると共に(左)、ヘモグロビン陽性細胞数が有意に減少する(右)。
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Associate Professor Shinjiro Hino
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Republished with permission of Elsevier Science & Technology Journals, from <i><a href="https://ashpublications.org/bloodadvances/article/5/9/2305/475840/LSD1-defines-erythroleukemia-metabolism-by">LSD1 defines erythroleukemia metabolism by controlling the lineage-specific transcription factors GATA1 and C/EBPα</a></i>, Kensaku Kohrogi, Shinjiro Hino, Akihisa Sakamoto, Kotaro Anan, Ryuta Takase, Hirotaka Araki, Yuko Hino, Kazutaka Araki, Tetsuya Sato, Kimitoshi Nakamura, and Mitsuyoshi Nakao, Blood Advances, 5(9), 2021; permission conveyed through Copyright Clearance Center, Inc.?
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