Figure 1. Activation of the human A2A receptor (IMAGE)

Tokyo Institute of Technology

Figure 1. Activation of the human A2A receptor

Caption

Activation of the human A2A receptor (shown in turquoise) in complex with a G protein consisting of the α, β, and γ subunits (shown in violet, light blue and bark blue, respectively), is exquisitely controlled by changes in dynamics and action of the ligand, highlighted in lime at the top of the figure. Activation pathways are observed to extend from the ligand binding site (lime) to the nucleotide binding site (yellow) in the G protein.

Credit

Cell

Usage Restrictions

None

License

Licensed content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.