転写制御領域における低メチル化と神経機能に重要な (IMAGE) Kumamoto University Caption (左)高メチル化されたDNA領域の数が神経細胞・非神経細胞共に患者群(BD)で健常者群(CT)と比較し低下している。 (右)精神・神経機能に重要なBDNF(brain-derived neurotrophic factor)受容体遺伝子(NTRK2)のメチル化状態。患者で高メチル化されている領域を上段に、患者・健常者それぞれのDNAメチル化状態を下段に示す。 Credit Professor Kazuya Iwamoto Usage Restrictions <p>Left: Fig. 1(b), Right: Fig. 2(d) of <a href="https://www.nature.com/articles/s41380-021-01079-0">Bundo, M. et.al., Molecular Psychiatry, 2021</a>. </p> <p>This image is made available under the terms of <a href="https://creativecommons.org/licenses/by/4.0/">CC by 4.0</a>. Any further distribution of this work must follow the terms of this license. </p> License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.