Heatmap (IMAGE)

New York University

Heatmap

Caption

(A) Heatmap showing a global decrease in H3K27me3 IP/IN signal in promoter of all genes but no change in H3K9me3. (B) H3K27me3 IP/IN signal for all promoters shown as scatter plot. (C) H3K27me3 IP/IN signal for all promoters broke down into quartiles and displayed as box-and-whisker plots. Error bars represent s.d. (D) Heatmap showing overall loss H3K27me3 IP/IN signal from 153 K27+ cluster 6 genes. (E) Heatmap showing overall loss H3K27me3 IP/IN signal from 82 K4+K27+ (bivalent) cluster 6 genes. (F) UCSC genome browser view of 6 H3K27me3- regulated E2F targets from (E) that lost H3K27me3 and gained H3K4me3 in the promoter region in Uhrf1hepKO livers.

Credit

Kirsten Sadler Edepli, NYU Abu Dhabi Associate Professor of Biology

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