The rescue effect of Btg2 overexpression in β-cells overexpressing miR-146b. (IMAGE)
Caption
Min6 cells were transfected with a plasmid containing the mouse Btg2 sequence (Btg2 OE) or a control plasmid (control) and co-transfected with miR-146b mimics or negative control. Seventy-two hours after transfection, apoptosis (by TUNEL) (A) and proliferation (by EdU) (B) were detected as described previously. Results are mean ± standard error of the mean for three experiments. *P < 0.05 and ***P < 0.001 versus mimics NC or miR-146b mimics + control.
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Genes & Diseases
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