CDC20 was up-regulated in human glioma tissues and correlated with the prognosis of glioma patients. (IMAGE)

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CDC20 was up-regulated in human glioma tissues and correlated with the prognosis of glioma patients.

Caption

(A) The expression level of the HMGN2 (mRNA sequencing) in low-grade gliomas (LGG) and glioblastoma multiforme (GBM) from GEPIA. (B) The expression level of the HMGN2 in different grades of glioma from CGGA-693. (C, D) The prognostic significance of CDC20 in glioma via TCGA and CGGA-693 databases. (E) Immunohistochemical staining was performed to evaluate CDC20 expression in glioma tissue samples. Scale bar, 50 μm. (F) Pearson correlation coefficient plots between HMGN2 and CDC20. (G) The overall survival time plot of patients in the high HMGN2/CDC20 expression group versus those in the low HMGN2/CDC20 expression group. All data were expressed as mean ± standard deviation. Student's t-test was performed to analyze significance; ∗P < 0.05, ∗∗P < 0.01, ∗∗∗P < 0.001, and ∗∗∗∗P < 0.0001.

Credit

Genes & Diseases

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