Single-cell landscapes between NB-BBM and non-metastatic groups. (IMAGE)

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Single-cell landscapes between NB-BBM and non-metastatic groups.

Caption

(A) UMAP of single-cell RNA sequencing data for all cells from 31 neuroblastoma patients. (B) Expression of typical cell type marker genes in 12 clusters. (C) The percentage of each of the 12 cell subpopulations in the neuroblastoma patient samples. (D) Differential profile of each of the 4 tumor cell subpopulations in the G1/G2/G3 groups. (E) Tumor cells in the G1/G2/G3 subgroups were analyzed for copy number variations (CNVs). (F) Differential genes in NB3 tumor cell subpopulations in the G1/G2/G3 group. (G) Pathway enrichment of NB3 tumor cell subpopulations in the G1/G2/G3 group. (H) Expression of 5 complex-related molecules in the oxidative phosphorylation pathway in the G1/G2/G3 group.

Credit

Genes & Diseases

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