Image 2 (IMAGE)

The Korea Advanced Institute of Science and Technology (KAIST)

Image 2

Caption

Figure 2. Identification of tumor transition state using single-cell RNA sequencing data from colorectal cancer. Using single-cell RNA sequencing data from colorectal cancer patient-derived organoids for normal and cancerous tissues, a critical transition was identified in which normal and cancerous cells coexist and instability increases (a-d). The critical transition was confirmed to show intermediate levels of major phenotypic features related to cancer or normal tissues that are indicative of the states between the normal and cancerous cells (e).

Credit

KAIST Laboratory for Systems Biology and Bio-Inspired Engineering

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