Figure 3 (IMAGE)

Institute for Basic Science

Figure 3

Caption

An artistic representation of the mutational “scar” left by translesion synthesis. When a train (replicative polymerase) encounters an obstacle, the passenger has to disembark and proceed around the obstacle on foot (error-prone translesion polymerase), leaving footprints (mutations). These mutations are detected by whole genome sequencing and mark the locations where the switch to a translesion polymerase occurred.

Credit

Institute for Basic Science

Usage Restrictions

Attribution Required

License

Original content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.