(IMAGE) Kumamoto University Caption This study successfully reproduced the developmental process of hematopoietic stem cells (HSCs) in an in vitro culture system using commercially available endothelial cell lines as feeder cells, without the serum. By adding just two signaling molecules, stem cell factor (SCF) and thrombopoietin (TPO), the researchers were able to induce transplantable HSCs. Credit Saori Morino-Koga, Minetaro Ogawa, Kumamoto University Usage Restrictions Only to be used in content reporting on this research. Credit must be given to the creator. License Original content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.