Illustration of typical and obese ob/ob mice (IMAGE)

University of Tokyo

Illustration of typical and obese ob/ob mice — Caption

Obese ob/ob mice eat excessively and are typically used for research into Type 2 diabetes. The mutated gene which causes increased appetite in ob/ob mice led to the discovery of the hormone leptin, which controls body fat by suppressing hunger and is lacking in the obese mice.

Credit

2023 Shinya Kuroda

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