plastic contraction wave (IMAGE)
Caption
Propagation of a plastic contraction wave within the tissue. (A) Evolution of the average junction tension in each cell. During simulations, the central two-round of cells (i.e., 7 cells at the center) are illuminated and thus activated at t=0 . (B, C) Quantitative heatmaps of junction tension (B) and myosin activity (C) during the propagation of the plastic contraction wave shown in (A). The solid black line indicates that such a wave propagates at a speed of ~1 round of cells per 2 minutes. (D) Simulated (red points) and experimentally observed (green belts) locations of the plastic wavefront, where the normalised myosin activity becomes higher than 0.2 . (E-H) Propagation of the plastic contraction wave is affected by different physical parameters, including the critical activation strain (E), contraction amplitude (F), viscoelasticity ((G), unit: N∙s∙m-1 ), and reaction time ((H), unit: s ).
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The University of Hong Kong
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