A team from Washington University School of Medicine in St. Louis and Northwestern University in Chicago has developed a device that may rescue people from overdose without bystander help. In animal studies, the researchers found that the implantable device detects an overdose, rapidly delivers naloxone to prevent death and can alert emergency first responders.

Scientists at Gladstone Institutes have worked out exactly how immune cells trigger scar-forming fibroblasts to become activated and cause fibrosis in the heart, and likely in other organs as well. Blocking the molecular signals between inflammation-causing immune cells and fibroblasts, they showed, can prevent this fibrosis.

Scientists have created a 3D-printed model to mimic the specific conditions that spur the spread of cancer cells. The model, published in the journal Life Science Alliance, allows researchers to study a process previously hidden from view and may open the door to new screening and treatment options for cancers at risk of spreading. 

Using two specialized microscopes invented at the Marine Biological Laboratory (MBL), a team of researchers from Japan and the MBL have developed a new method to measure the forces that keep the nucleus centered within a living cell. Their report was published on Oct. 18 in Proceedings of the National Academy of Sciences.